Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known Some side effects of hydroxychloroquine may occur that usually do not need medical attention. Plaquenil how long to work What tyoe of arthritis is plaquenil Turmeric and plaquenil Can i take vitamin d with plaquenil In addition, since responses to stress can cause physical symptoms such as headache, increased pain, and muscle tension, try to practice stress management skills. There are some stressors that you can control, and there are some that are simply out of your hands. Feeling that others can hear your thoughts feeling, seeing, or hearing things that are not there fever with or without chills general feeling of tiredness or weakness headache inability to move the eyes increased blinking or spasms of the eyelid joint or muscle pain Plaquenil can make you completely blind! *Legitimate looking vitamins I take to help remediate it I took Plaquenil for over 13 years and it caused me and 6 in every 1000 patients, new research shows to have toxic maculopathy it caused. *re even if you quit taking the drug, it can continue to damage the eye until blindness occurs. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. Can plaquenil cause headaches Plaquenil - Uses, Side Effects, Interactions -, Hydroxychloroquine Oral Route Side Effects - Mayo Clinic Chloroquine phosphate 250 mg side effectsLipusu liposome chloroquine Thanks for your advice, Shani. The headaches were just bad headaches and stopped when I started taking Plaquenil at night instead of the morning. The blurred vision came separately and went a day or two after I stopped the Plaquenil again. As it happens, my GP phoned me today about something else and I told her about this. Plaquenil headache. Lupus Forums at The Lupus Site. PLAQUENIL Side Effects, Reviews by Patients -. Common and Rare Side Effects for Plaquenil Oral. Plaquenil can cause serious side effects when used in high doses for chronic diseases such as RA over the long term. The New Zealand Dermatological Society recommends that to decrease the risk of retina damage, no more than 200mg of Plaquenil should be taken a day, and a dose of 400mg per day should be taken no longer than a few weeks. Maybe, he can give you something to help with the headaches. Also, Plaquenil can take up to 6 months before you really start to see improvement from the drug. If you have any more questions please feel free to ask away and I hope that you can get your headaches under control. Then rest in a darkened room. Remember also to keep hydrated.being slightly dehydrated can trigger headaches and migraines. I still take Plaquenil and have been on them since 2006. The migraines are no better or worse than before. So in my experience, the Plaquenil is not a problem for me.