At first it seemed like it helped now I feel the same as before I started taking the medicine other than the fact that none of my clothes fit and there is a lot more of me to carry around. Anyone know if I quit taking it if the weight will fall back off I started Hydroxychloroquine 2 weeks ago. One week in and I thought this may just work, except for the ‘extra itchiness’ I seemed to get every night. Long term plaquenil therapy Pool chloroquine tablet How do plaquenil look Avloclor 250mg chloroquine phosphate Aug 14, 2017 Plaquenil can cause serious side effects when used in high doses for chronic diseases such as RA over the long term. The New Zealand Dermatological Society recommends that to decrease the risk of retina damage, no more than 200mg of Plaquenil should be taken a day, and a dose of 400mg per day should be taken no longer than a few weeks. Hydroxychloroquine oral tablet doesn’t cause drowsiness, but it can cause other side effects. More common side effects. The more common side effects that can occur with hydroxychloroquine include Fatigue is part of malaria, which is the normal use of this medication. Here are the side effects be sure your doctor looks at this. Get emergency medical help if you have any of these signs of an allergic reaction while taking hydroxychloroquine hives; difficulty breathing; swelling of your face, lips, tongue, or throat. I was prescribed this drug to ease my ra disease, I was taking 400mg per day which was to last for 3 months then reduced to 200mg. Right before I hit the two week mark, I woke up with my heart racing and continued feeling my heart flutter all day and I just felt week and tired. After msging Rheum, decided to stop taking meds to see how I feel and continue with the AIP to handle symptoms and try to work at ‘healing from inside out! Time will tell and I’m eager to see how much the AIP is helping once odd meds. Does hydroxychloroquine cause fatigue Does Plaquenil make you tired? DailyStrength, Hydroxychloroquine Side Effects, Dosage, Uses, and More Chloroquine pigmentationGene rdh12 chloroquine retinopathyAdverse effects of chloroquine I started on the Plaquenil a little over a week ago. Not much in the way of side effects. Some minor stomach stuff but that could be normal and not related to the Plaquenil. I started at 200mg and increased to 400mg after a week. Andie213, my fatigue has been frustrating for me as well. Experiences taking Plaquenil for Fatigue and Muscle Pain. - Inspire. Hydroxychloroquine - thigh muscle weakness?. Drug spotlight on hydroxychloroquine Lupus Foundation of America. Plaquenil Side Effects by Likelihood and Severity INFREQUENT side effects. If experienced, these tend to have a Severe expression. WebMD does not provide medical advice, diagnosis or treatment The way I understand it the plaquenil causes some CNS irritability. I think I have a little of it but I will just hang in there cause I had my dosage increased from 200 to 400 and saw results starting after 1 month. For me the relief of some of the symptoms has been very slight improvement that has increased slowly over time. Aug 30, 2016 Several studies have shown that hydroxychloroquine positively affects insulin and glucose metabolism.4,7,8,10,11,12,13 In fact, the highlighted point of the present study was the effects of hydroxychloroquine on glucose control in the prediabetes, state independent of its effect on body weight and composition as well as on the lipid profile.