Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known Some side effects of hydroxychloroquine may occur that usually do not need medical attention. Lyme biaxin plaquenil Hydroxychloroquine & methotrexate SIDE EFFECTS. The following adverse reactions have been identified during post-approval use of PLAQUENIL or other 4-aminoqunoline compounds. Because these reactions are reported voluntarily from a population of uncertain size, it is not always possible to reliably estimate their frequency or establish a causal relationship to drug exposure. And now I'm allergic to Plaquenil, which is actually fine by me because my psoriasis, which is normally very well controlled, erupted a few days before the hives and swelling started. The Plaquenil and sulfasalazine allergies manifested exactly the same way, though the sulfa reaction was a bit more severe. I think I'm allergic to my plaquenil.i get fits of extreme itching all over but mostly arms and legs. The only way to get relief is putting them in very cold water and taking anti histamines. Is this normal? Does anyone else get this? And does it mean the plaquenil isn't working against the RA. 0 likes, 7 replies Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. Allergic to plaquenil Plaquenil Oral Uses, Side Effects, Interactions, Pictures., Sulfa & Plaquenil allergies related? DailyStrength Hydroxychloroquine bleedingIs atovaquone a chloroquinePlaquenil and vision side effectsCan you take plaquenil and unithroid Grandson not allergic to Plaquenil He had reactions to it. He has a rheumatologist at Cedars Sinai they took him off Generic Plaquenil and put him on brand he does much better with that Generic drugs are ok in most cases but this needs to be as good as it gets Allergic to Plaquenil lupus. Allergic to plaquenil Rheumatoid Arthritis Forums Patient. Allergic reaction to Plaquenil Lupus Forums at The Lupus Site. Some of the dosage forms listed on this page may not apply to the brand name Plaquenil. For the Consumer. Applies to hydroxychloroquine oral tablet. Along with its needed effects, hydroxychloroquine the active ingredient contained in Plaquenil may cause some unwanted effects. Although not all of these side effects may occur, if they do occur. Aug 29, 2014 One of the reasons that physicians feel comfortable in prescribing Plaquenil is its low risk to benefit ratio. This means that the side effects of Plaquenil are mild and infrequent compared with its potential benefits. As with any medication, allergic reactions including skin rashes and non-allergic reactions can occur. With Plaquenil, however, the most commonly prescribed anti-malarial, this sort of damage occurs only in 1 out of 5,000 people who take the drug for five years or more. For this reason though, it is important that you see an ophthalmologist for an exam before starting to take an anti-malarial medication for your lupus.