It does not include any risks conferred by pharmaceutical agents or their metabolites in breast milk. Every drug has specific information listed in its product literature. Is chloroquine a lysosome Chloroquine blood plasma ratio Chloroquine phosphate is in a category of medicine called antimalarials and amebicides. There are roughly 300 instances of extreme malaria within the United States each year, most of them acquired from travel to malaria-endemic nations. PLAQUENIL is not effective against chloroquine-resistant strains of P. falciparum. Children are especially sensitive to the 4-aminoquinoline compounds. A number of fatalities have been reported following the accidental ingestion of chloroquine, sometimes in relatively small doses 0.75 g Drug interactions. What are the potential side. effects of chloroquine? Chloroquine is a relatively well-tolerated. medicine. The most common adverse reactions reported are stomach pain, nausea, vomiting, and headache. These side effects can often be lessened by taking chloroquine with food. Chloroquine may also cause itching in some people. Title 21, Part 201.57 (9)(i) of the Code of Federal Regulations lists specific requirements regarding the labeling of drugs with respect to their effects on pregnant populations, including a definition of a "pregnancy category". The British National Formulary used to provide a table of drugs to be avoided or used with caution in pregnancy, and did so using a limited number of key phrases, but now Appendix 4 (which was the Pregnancy table) has been removed. American law requires that certain drugs and biological products must be labelled very specifically. Chloroquine fda pregnancy category Chloroquine Oral Uses, Side Effects, Interactions, Pictures., PLAQUENIL® - Food and Drug Administration Drug instead of hydroxychloroquineHydroxychloroquine in breastfeeding Plaquenil is the brand name for the prescription drug hydroxychloroquine. It's used to treat and prevent malaria infection, and to reduce symptoms and progression of autoimmune diseases such as lupus, rheumatoid arthritis, and others. Malaria is spread by mosquitoes. Plaquenil Hydroxychloroquine - Side Effects, Dosage.. Medicines for the Prevention of Malaria While Traveling.. Hydroxychloroquine MotherToBaby. Chloroquine phosphate may cause an upset stomach. Take chloroquine phosphate with food. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Use chloroquine phosphate exactly as directed. Do not use more or less of it or use it more often than prescribed by your doctor. US FDA pregnancy category Not assigned Risk Summary Animal studies show that this drug passes rapidly across the placenta. It accumulated selectively in the melanin structures of the fetal eyes and was retained in the ocular tissues for 5 months after the drug had been eliminated from the rest of the body. Technically, Plaquenil does not have an official pregnancy Category rating, as is common with older medications. However, most sources consider it to be a pregnancy Category C medication. In animal studies, it was shown that Plaquenil crosses the placenta and accumulates in the eyes of the fetus and remains there for several months.