One such commonly used medication for dermatologic and rheumatologic inflammatory conditions is hydroxychloroquine (Plaquenil), a chloroquine derivative. It is used to treat many diseases including malaria, rheumatoid arthritis and systemic lupus erythematosus. Plaquenil tongue Plaquenil allergic rash Chloroquine tlr inhibitor Mar 15, 2019 Other reported visual symptoms include the following Dimness. Flickering or flashing lights of yellow. Green or red haloes. Cycloplegia. Amblyopia. Diplopia. Blindness. Photophobia. Oculogyric crisis. Plaquenil toxicity isn’t even in the top 10, or the top 100” if you’re looking at incidence, he said. “It’s a pretty rare thing.” Nevertheless, he urged doctors to master the Academy’s new guidelines, because the effects from chloroquine and hydroxychloroquine, when they do occur, are severe and often irreversible. Jun 30, 2015 Take this medication with a meal or a glass of milk to prevent stomach upset. Common side effects include nausea, loss of appetite, headache, and diarrhea. Plaquenil can cause blurred vision and dizziness. Do not drive or operate heavy machinery until you know how it affects you. It is imperative that patients and physicians are aware of and watch for this drug’s ocular side effects. Retinal toxicity from hydroxychloroquine is rare, but even if the medication is discontinued, vision loss may be irreversible and may continue to progress. Plaquenil toxicity symptoms Plaquenil Toxicity Screening - Retina Group of New York, Rx Side Effects New Plaquenil Guidelines and More - American. Can plaquenil raise blood pressureHow long to take plaquenil for lupus End stage hydroxychloroquine toxicity leads to widespread RPE and retinal atrophy with a loss of central vision, peripheral vision, and night vision. Hydroxychloroquine Plaquenil Toxicity and Recommendations.. Plaquenil - Side Effects, Uses, Dosage, Overdose, Pregnancy.. Hydroxychloroquine MedlinePlus Drug Information. Overdose symptoms may include Headache. Drowsiness. Vision changes. Slow heart rate. Chest pain or heavy feeling. Pain spreading to the arm or shoulder. Nausea. Sweating. Seizure. Shallow breathing. Breathing that stops. If the patient manifests the toxicity symptoms of Plaquenil, the standard of care is to stop taking the medication and to change the medication the patient is taking. Possible coordination with the dermatologist or the rheumatologist may be required for the continuous care. When using both these tools, keep in mind the following from Melles and Marmor’s recent study 1. “Retinal toxicity from hydroxychloroquine use cannot be completely prevented, but effective screening should recognize retinal toxicity before symptoms or significant risk of central vision loss appear ie.