Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known Some side effects of hydroxychloroquine may occur that usually do not need medical attention. Malaria plaquenil Plaquenil and sjogren's syndrome Doctors give unbiased, trusted information on whether Plaquenil can cause or treat Weight Gain Dr. Valdez on hydroxychloroquine and weight gain Depression can cause weight gain and loss, but alopecia not a common sign of depression. Plaquenil and other antimalarials are the key to controlling lupus long-term, and some lupus patients may be on Plaquenil for the rest of their lives. For this reason, you can think of antimalarials as a sort of “lupus life insurance.” Plaquenil Side Effects by Likelihood and Severity INFREQUENT side effects. If experienced, these tend to have a Severe expression. Weight Loss; Full Drug Information. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. Plaquenil losing weight Despite Plaquenil dosing recommendations, retinal toxicity., Plaquenil What You Need to Know - Kaleidoscope Fighting Lupus Plaquenil and psychosis SAN FRANCISCO – Hydroxychloroquine Plaquenil dosing based on actual body weight – instead of ideal weight – is appropriate for patients with systemic lupus erythematosus SLE, according to a review of 686 lupus patients at Johns Hopkins University in Baltimore. Most were dosed by actual weight, 6.5 mg/kg up to a maximum of 400 mg/day. ACR Actual-weight hydroxychloroquine dosing works in SLE.. Common and Rare Side Effects for Plaquenil Oral. Plaquenil Oral Uses, Side Effects, Interactions, Pictures.. Loss of balance or coordination, blurred vision, light sensitivity, seeing halos around lights, pale skin, easy bruising or; bleeding, confusion, unusual thoughts or behavior, or; seizures convulsions. Dosage for Plaquenil. The adult dose of Plaquenil to suppress malaria is 400 mg on the same day each week. Note This document contains side effect information about hydroxychloroquine. Some of the dosage forms listed on this page may not apply to the brand name Plaquenil. For the Consumer. Applies to hydroxychloroquine oral tablet. Along with its needed effects, hydroxychloroquine the active ingredient contained in Plaquenil may cause some unwanted effects. By the old standards, obese people, if dosed by their actual weight, could be overmedicated, Dr. Marmor said. If you’re short, the standard prescription of 200 mg of Plaquenil, twice daily, is too much, he said. The recommended dosage is no more than 6.5 mg/kg/day, using the standard known as “ideal weight,” which factors in height. Dr.