While no vaccine or antiviral treatments are yet available, part of the virus’s impact is that infected people can develop pneumonia. Now, researchers in Shanghai are aiming to evaluate the efficacy and safety of Plaquenil (hydroxychloroquine, Sanofi-Aventis) to treat that pneumonia. Chloroquine phosphate malaria side effects Hydroxychloroquine hypercalcemia Hydroxychloroquine int One of the most serious side effects is a toxicity in the eye generally with chronic use. People taking 400 mg of hydroxychloroquine or less per day generally have a negligible risk of macular toxicity, whereas the risk begins to go up when a person takes the medication over 5 years or has a cumulative dose of more than 1000 grams. Plaquenil Side Effects by Likelihood and Severity INFREQUENT side effects. If experienced, these tend to have a Severe expression. A Disorder Of The Retina Of The Eye; Uncontrolled eye movements unsteadiness, trembling, or other problems with muscle control or coordination vomiting Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional. Call your doctor for medical advice about side effects. Additionally, adverse ocular affects are rare, but patients taking Plaquenil require more stringent optometric oversight.5mg/kg/d of their actual weight, or have other risk factors. The COVID-19 study is only looking into a five-day course, so it shouldn’t be alarming to optometrists, says Sara Wedimayer, OD, an optometrist with the Ann Arbor Healthcare System’s Veterans Administration and a clinical instructor at the University of Michigan. Effect of plaquenil on eyes Long-Term Side Effects of Plaquenil for Rheumatoid., Common and Rare Side Effects for Plaquenil Oral Chloroquine against malaria1989 honduras chloroquine Eye damage due to Plaquenil is not common,” he says. “Rarely will anybody who has good vision and minimal symptoms develop loss of central vision or ability to read if annual screening is done and visual are symptoms reported as soon as they occur so the medication can be stopped if toxicity occurs. Protecting your eyesight when taking Plaquenil Lupus.. Hydroxychloroquine Oral Route Side Effects - Mayo Clinic. What can Hydroxychloroquine Plaquenil do to my eyes?. Note This document contains side effect information about hydroxychloroquine. Some of the dosage forms listed on this page may not apply to the brand name Plaquenil. For the Consumer. Applies to hydroxychloroquine oral tablet. Along with its needed effects, hydroxychloroquine the active ingredient contained in Plaquenil may cause some unwanted effects. I think it’s good for optometrists to be aware that this study is going on, as I’m sure they’ll be asked questions, but even if 400mg of Plaquenil a day for five days ends up being regularly used for those with pneumonia from COVID-19, it’s very unlikely that those patients would have any significant eye-related side effects or toxicity. The effects lupus may have in and around the eyes include changes in the skin around the eyelids, dry eyes, inflammation of the white outer layer of the eyeball, blood vessel changes in the retina, and damage to nerves controlling eye movement and affecting vision. As a precaution, people treated with Plaquenil should get a baseline eye.