Chloroquine maculopathy ppt

Discussion in 'Canadian Pharcharmy Online' started by DZZR, 26-Feb-2020.

  1. Reggun User

    Chloroquine maculopathy ppt


    Chloroquine has been extensively used in mass drug administrations, which may have contributed to the emergence and spread of resistance. It is recommended to check if chloroquine is still effective in the region prior to using it.

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    Purpose. To evaluate the role of spectral-domain optical coherence tomography SD-OCT in early detection of Chloroquine maculopathy in rheumatoid arthritis RA patients. iMethods/i. 40 left eyes of 40 female rheumatoid arthritis patients who received treatment chloroquine for more than one year were recruited in the study. Recent studies estimate that about 1% of patients develop toxic maculopathy after 5 years of treatment with plaquenil or chloroquine. The risk of maculopathy is associated with cumulative dose level of 1,000 grams and it usually takes 5-7 years for patients on the standard treatment of 250-400 milligrams per day to reach that level. Usual Adult Dose for Malaria Prophylaxis. 500 mg chloroquine phosphate 300 mg base orally on the same day each week Comments-If possible, suppressive therapy should start 2 weeks prior to exposure; if unable to start 2 weeks before exposure, an initial loading dose of 1 g chloroquine phosphate 600 mg base may be taken orally in 2 divided doses, 6 hours apart.

    The Centers for Disease Control and Prevention recommend against treatment of malaria with chloroquine alone due to more effective combinations. In areas where resistance is present, other antimalarials, such as mefloquine or atovaquone, may be used instead.

    Chloroquine maculopathy ppt

    Hydroxychloroquine-induced bull's eye maculopathy - The., H35.381-383 Toxic Maculopathy Of Retina - Decision-Maker PLUS

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  6. Abstract. Background The American Academy of Ophthalmology recommendations on screening for chloroquine CQ and hydroxychloroquine HCQ retinopathy are revised in light of new information about the prevalence of toxicity, risk factors, fundus distribution, and effectiveness of screening tools.

    • Recommendations on Screening for Chloroquine and..
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    • Chloroquine - FDA prescribing information, side effects..

    Chloroquine is a potent drug used for the treatment of various diseases, including malaria and a range of connective tissue disorders. Chloroquine retinopathy is an important complication that may appear even years after cessation of the drug, presenting with impaired visual acuity, central vision loss and progressive damage that could result in irreversible blindness. Sep 15, 2014 Hydroxychloroquine and chloroquine work in a similar way as antimalarial medication with different therapeutic and toxic doses and produce a similar pattern of retinopathy. HCQ appears to be considerably less toxic to the retina than CQ, possibly because chloroquine passes the blood – retinal barrier easier. Symptoms PowerPoint Presentation Retinopathy with reduced visual acuity - accumulation of drug in melanin rich tissues Bulls eye maculopathy –reversible Ototoxicity irreversible Myopathy, cardiomyopathy, peripheral neuropathy, suicidal tendency occurs Periodic neurological and retinal check up should be done Adverse effects of chloroquine cont

     
  7. uxusco Moderator

    Hydroxychloroquine is a quinoline medicine used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Plaquenil Prices, Coupons & Patient Assistance Programs. Hydroxychloroquine Oral Route Description and Brand Names. Hydroxychloroquine - Wikipedia
     
  8. santa_ New Member

    Plaquenil is the brand name for the prescription drug hydroxychloroquine. Plaquenil Hydroxychloroquine Uses, Dosage, Side Effects. Stomach problems with Plaquenil • Johns Hopkins Arthritis Center Taking Plaquenil for Rheumatoid Arthritis
     
  9. Ihor108 XenForo Moderator

    Hydroxychloroquine and Retinal Screening Retinal screening service will be provided by STH Ophthalmology department As patients are started on hydroxychloroquine, they will have a baseline retinal screen usually at 3 months but certainly within 12 months of starting, organised by the specialist. The specialist will also arrange a follow up retinal screen after 5 years

    Protecting your eyesight when taking Plaquenil Lupus.