I've been taking Plaquenil since February and have not had any flashes. I never had them associated with plaquenil, but I think I might remember someone else asking a similar question here at some time about plaquenil and hot flashes. You could either call your pharmacist or check the list of side effects they list when you pick up your next script . Hot flashes can come from Lupus itself..I don't remember if that is a direct cause or if its the lupus playing with hormones that makes then happen. Doea plaquenil affect the immune system Plaquenil ibd Hi all- I've been on Plaquenil 400 mg daily for just about two months now. Shortly after starting I noticed a marked increase in the number of hot flashes/night sweats and anything at any time can irritate the heck out of me. PLAQUENIL is a synthetic Quinilone, belongs in the Floro Quinilone family which has a black box warning by the FDA. I did not this at the time i took it. Previously had bad tendon damage with Cipro. Hot flashes start when blood vessels near the skin's surface widen to cool off, making you break out in a sweat. Some women have a rapid heart rate or chills, too. When they happen while you. I'd probably ask my rheumy about them next time I'm in if I were you. I had LOTS of hot flashes before my lupus became more controlled. Plaquenil hot flashes Rheumatoid Arthritis 17 Signs of Serious Complications, PLAQUENIL Side Effects, Reviews by Patients - Plaquenil ibuprofen interactionPlaquenil muscle weakness Hot flashes, or as I call 'em "Power Surges" from plaquenil. Could be. I take lots a meds besides plaquenil. I had my doc do a blood test to see if I was starting menapause because I have power surges all the time. It was negative, so its one of the meds. Hot flashes from Plaquenil - Sjogren's World. Hot Flashes Why They Happen, Treatment, Prevention. Lupus Symptoms, Diagnosis and Treatments. StacyLee, I'm not sure about plaquenil and hot flashes. I never had them associated with plaquenil, but I think I might remember someone else asking a similar question here at some time about plaquenil and hot flashes. you could either call your pharmacist or check the list of side effects they list when you pick up your next script. Menopausal symptoms. Applying wild yam cream to the skin for 3 months does not seem to relieve menopausal symptoms such as hot flashes and night sweats. It also does not seem to affect levels of hormones that play a role in menopause. Menopausal hot flashes are sudden feelings of intense body heat that can occur during the day or night. Night sweats are periods of heavy sweating, or hyperhidrosis, associated with hot flashes that occur at night. They can often wake women up from sleep.