When it’s worn away or damaged, nerves can deteriorate, causing problems in the brain and throughout the body. Axons also connect neurons to other cells, such as muscle cells. What does hydroxychloroquine treat What elements are in chloroquine What is an alternative medication to plaquenil Chloroquine phosphate for lupus Hydroxychloroquine oral tablet doesn’t cause drowsiness, but it can cause other side effects. More common side effects. The more common side effects that can occur with hydroxychloroquine include Summary Weight loss is found among people who take Hydroxychloroquine sulfate, especially for people who are female, 2-9 old, have been taking the drug for 1 - 2 years, also take medication Enbrel, and have Juvenile rheumatoid arthritis. Plaquenil can cause serious side effects when used in high doses for chronic diseases such as RA over the long term. The New Zealand Dermatological Society recommends that to decrease the risk of retina damage, no more than 200mg of Plaquenil should be taken a day, and a dose of 400mg per day should be taken no longer than a few weeks. Myelin is made of membrane layers that cover an axon. Some axons are extremely short, while others are 3 feet long. Myelin protects the axons and helps carry axon messages as quickly as possible. Does hydroxychloroquine cause demyleination Demyelination in rheumatic diseases - PubMed Central PMC, Will you have Weight loss with Hydroxychloroquine sulfate. How often do you need labs on plaquenilEfectos secundarios de plaquenil 200 mgWhy hydroxychloroquine for porphyria cutanea tardaPlaquenil and respiratory problems Plaquenil Side Effects by Likelihood and Severity INFREQUENT side effects. If experienced, these tend to have a Severe expression. WebMD does not provide medical advice, diagnosis or treatment Common and Rare Side Effects for Plaquenil Oral. Long-Term Side Effects of Plaquenil for Rheumatoid Arthritis. Medicines for the Prevention of Malaria While Traveling.. Diagnosis can be established by confirming JC virus DNA in the. requires brain biopsy with the histopathologic triad of demyelination, bizarre. Hydroxychloroquine also known as plaquenil is a medication. so we did not think this was the cause of his PML although it may have caused him to worsen. Hydroxychloroquine belongs to a group of medicines known as antimalarials. It works by preventing or treating malaria, a red blood cell infection transmitted by the bite of a mosquito. However, this medicine is not used to treat severe or complicated malaria. A demyelinating disease is any disease of the nervous system in which the myelin sheath of neurons is damaged. This damage impairs the conduction of signals in the affected nerves. In turn, the reduction in conduction ability causes deficiency in sensation, movement, cognition, or other functions depending on which nerves are involved.