Excipient information presented when available (limited, particularly for generics); consult specific product labeling. Tablet, Oral, as phosphate: Generic: 250 mg [equivalent to chloroquine base 150 mg], 500 mg [equivalent to chloroquine base 300 mg] Binds to and inhibits DNA and RNA polymerase; interferes with metabolism and hemoglobin utilization by parasites; inhibits prostaglandin effects; chloroquine concentrates within parasite acid vesicles and raises internal p H resulting in inhibition of parasite growth; may involve aggregates of ferriprotoporphyrin IX acting as chloroquine receptors causing membrane damage; may also interfere with nucleoprotein synthesis Rapid and almost complete Widely in body tissues including eyes, heart, kidneys, liver, leukocytes, and lungs where retention is prolonged Partially hepatic to main metabolite, desethylchloroquine Urine (~70%; ~35% as unchanged drug); acidification of urine increases elimination; small amounts of drug may be present in urine months following discontinuation of therapy Serum: Oral: Within 1-2 hours 3 to 5 days ~55% Malaria: Treatment of uncomplicated malaria due to susceptible strains of Plasmodium vivax, Plasmodium malariae, Plasmodium ovale, and Plasmodium falciparum; prophylaxis of malaria (in geographic areas where chloroquine resistance is not present). Chloroquine interfer nucleic acid biosynthesis Hydroxychloroquine half life Lysosomal inhibitor chloroquine Can plaquenil help with small fiber neuropathy Chloroquine Phosphate, USP, is a 4aminoquinoline compound for oral administration. It is a white, odorless, bitter tasting, crystalline substance, freely soluble in water. Chloroquine Phosphate Tablets are an antimalarial and amebicidal drug. Each tablet, for oral administration, contains 250 mg chloroquine phosphate equivalent to 150 mg. For aquarium use only. This product is designed to be used in a bare bottom quarantine tank and it is not reef safe. In most cases, 250 mg tablets have an equivalence of 150 mg chloroquine base, and 500 mg tablets have an equivalence of 300 mg chloroquine base. Although the purity mentioned above is generally accurate, it would be best to verify the chloroquine base contained in the tablets of your choice in order to be able to properly calculate the exact. Do not use for the treatment of complicated malaria (high-grade parasitemia and/or complications [eg, cerebral malaria, acute renal failure]) or for malaria prophylaxis in areas where chloroquine resistance occurs (resistance to chloroquine is widespread in P. Additional data may be necessary to further define the role of chloroquine in the treatment of this condition. Limitations of use: Chloroquine does not prevent relapses in patients with vivax or ovale malaria (not effective against exoerythrocytic forms). Extraintestinal amebiasis: Treatment of extraintestinal amebiasis. Data from a prospective, randomized, controlled, double-blind clinical trial supports the use of chloroquine in the treatment of discoid lupus erythematosus . Chloroquine phosphate 250 mg tablets Chloroquine Professional Patient Advice -, Chloroquine Phosphate 250 mg x 50 Tablets for Marine. Chloroquine and beclinPlaquenil effectiveness lupusSensorineural hearing loss and plaquenil Chloroquine phosphate tablets, Chloroquine phosphate, USP, is a 4-aminoquinoline compound for oral administration. It is a white, odorless, bitter tasting, crystalline substance, freely soluble inwater. Chloroquine phosphate tablets are an antimalarial and amebicidal drug. Chloroquine - FDA prescribing information, side effects.. Chloroquine phosphate REEF2REEF Saltwater and Reef.. Chloroquine - Wikipedia. Chloroquine Phosphate-250 mg 250mg - 10 Tablets Tablet Chloroquine drug information. Find its price or cost, dose, when to use, how to use, side effects, adverse effects, substitutes. It is. Rising had chloroquine phosphate tablets on shortage due to manufacturing delays related to obtaining raw materials. Available Products. Chloroquine tablet, Rising Pharmaceuticals, 250 mg, 50 count, NDC 64980-0177-50; Chloroquine tablet, Rising Pharmaceuticals, 500 mg, 25 count, NDC 64980-0178-02; Estimated Resupply Dates. Tablets containing 500 mg chloroquine phosphate USP, equivalent to 300 mg of chloroquine base, bottles of 25 NDC 0024-0084-01. White, film-coated convex, discoid tablet, ½ inch in diameter with an uncoated core, printed in black ink with a stylized “W” on one side and an “A77” on the other side.