Hydroxychloroquine is available as the brand-name drug Plaquenil. Generic drugs usually cost less than the brand-name version. Hydroxychloroquine may be used as part of a combination therapy. Chloroquine against malaria Plaquenil for hives Hydroxychloroquine and hearing loss Introduction Hydroxychloroquine Plaquenil® is an antimalarial agent which is approved for rheumatoid arthritis, systemic lupus erythematosis, discoid lupus erythematosis, prophylaxis and treatment of acute malaria, and photodermatosis 1. In the Netherlands it has been approved since 1966. I mentioned ringing in my ears to my rheumy a few months back. He had me go to an ENT to rule out Meniere's. They told me that plaquenil can cause it, but he did not think that it was that. So, anyway, after my appt. they determined that I have severe high frequency hearing loss and that is what is causing the ringing in my ears. Plaquenil is the brand name of hydroxychloroquine, a drug used to prevent or treat malaria 2. Plaquenil is also used for long-term treatment of autoimmune diseases such as rheumatoid arthritis RA and systemic lupus erythmatosis. Hydroxychloroquine is used to treat lupus erythematosus and rheumatoid arthritis. It isn’t fully understood how this drug works to treat lupus erythematosus or rheumatoid arthritis. That means you may need to take it with other drugs. It treats malaria by killing the parasites that cause the disease. Hydroxychloroquine ears Hydroxychloroquine Side Effects, Dosage, Uses, and More, Plaquenil and tinnitus DailyStrength Hydroxychloroquine sulfate tablets usp 200 mg usesEye exam when taking plaquenilHydroxychloroquine 200 mg tab sanPlaquenil lowers blood sugarPlaquenil medscape Applies to hydroxychloroquine oral tablet. Along with its needed effects, hydroxychloroquine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine Hydroxychloroquine Side Effects Common, Severe, Long Term.. Long-Term Side Effects of Plaquenil for Rheumatoid Arthritis.. Will you have Tinnitus with Plaquenil - eHealthMe. Hearing problems, such as ringing or ticking in the ears, or hearing changes Plaquenil may have toxic effects on your inner ear Loss of balance, coordination, room spinning, or other vertigo. Summary Tinnitus is found among people who take Hydroxychloroquine sulfate, especially for people who are female, 60+ old, have been taking the drug for 1 month, also take medication Enbrel, and have Insomnia. Hydroxychloroquine is in a class of drugs called antimalarials. It is used to prevent and treat acute attacks of malaria. It is also used to treat discoid or systemic lupus erythematosus and rheumatoid arthritis in patients whose symptoms have not improved with other treatments.