It's the first drug most doctors prescribe after you’re diagnosed. It will help ease symptoms like joint pain, fatigue, redness, and swelling. Hydroxychloroquine prescribing information pdf Lysosomal degradation inhibitor chloroquine Fortunately, the problems seen by people taking this medication are usually very mild. Serious side effects are rare. Overall, most people who have any noticeable side effects from hydroxychloroquine experience diarrhea or nausea. These usually get better after the person adjusts to the medication, and taking the drug with food can help, as well. Does anyone know if hydroxychloroquine and methotrexate can cause weight loss day, been taking for over a year now but although it helps with some of the pain. I have to have steroid. In the case of methotrexate hair loss, however, you may have more shedding than normal. Hair loss occurs gradually over time and isn’t usually drastic. In other words, you’re not likely to lose patches of hair. Speak with your doctor if you’re experiencing severe hair loss or if your hair is falling out in clumps. Methotrexate interrupts the process that causes RA inflammation, which damages your joints and organs over time. It may also help prevent damage to your organs and joints. Does hydroxychloroquine always help when taking methotrexate Hydroxychloroquine Plaquenil -, Does anyone take methotrexate and hydroxychloroquine. - NRAS The avgerage dosage a person takes of plaquenil This will help you avoid skin reactions. It can take 3 to 6 weeks to start to feel your methotrexate work. It takes even longer -- 12 weeks -- to get the full effects. Your doctor will test your blood often to check on how well your treatment works and to make sure it’s safe for organs such as your liver. How Does Methotrexate Treat Rheumatoid Arthritis? - WebMD. Methotrexate Hair Loss When and Why It Occurs and What.. Hydroxychloroquine Side Effects, Dosage, Uses, and More. My rheumatologist put me on prednisolone reduced doses over in 3 months until the methotrexate starts working once a week of 15mg for 2 weeks, 20mg once a week indefinitely. Plaquenil 300mg daily. I also take Vit D daily and 5mg folic acid once a week plus curcumin and fish oil I have been taking it all with breakfast for the last 8 days. Introduction. Reaching remission in early RA is crucial for ameliorating current complaints and preventing future functional loss is recommended as part of the first treatment in early RA by the EULAR and the ACR due to its favourable balance in effectiveness, safety profile and costs can be given as monotherapy or in combination with other conventional synthetic DMARDs. I have been taking hydroxychloroquine for 4 years for RA and it has stopped me from constantly being ill. My Rheumo wanted to change my meds to methotrexate which I was not happy about and refused.