Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known Some side effects of hydroxychloroquine may occur that usually do not need medical attention. Does plaquenil suppress the immune system Ufo sign plaquenil Hydroxychloroquine 200 mg tab san Ara patient information hydroxychloroquine Aug 30, 2011 The deposits affect the outer retina, photoreceptor layer, and the RPE, but preserve the inner retina. Prevalence Although hydroxychloroquine retinal toxicity is thought to be rare, recent studies suggest it may have a higher prevalence than previously recognized. Hydroxychloroquine is a commonly used immunosuppressive agent in the treatment of various autoimmune diseases. Despite lesser systemic toxicity compared to other drugs, it can cause severe retinal dysfunction and loss of vision. Retinal toxicity can occur as a side effect of long-term hydroxychloroquine therapy. Rarely, hydroxychloroquine can affect the bone marrow leading to reduced white blood cells leukopenia or platelets thrombocytopenia and abnormal red blood cells. Rare but potentially serious eye toxicity can occur. This toxicity affects a part of the eye called the retina and can lead to color blindness and even loss of vision. An. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. How does plaquenil affect the retina Treating Lupus with Anti-Malarial Drugs Johns Hopkins Lupus., Effect of Hydroxychloroquine on the Retinal Layers A. Trametinib hydroxychloroquinePlaquenil and dental extractionsIs plaquenil making my skin age and wrinkle fastHydroxychloroquine dose in rheumatoid arthritisPlaquenil vs hydroxychloroquine Wrong Hydroxychloroquine Dose Is Common, Putting Eyes at Risk. Up to half of patients treated with the arthritis drug hydroxychloroquine Plaquenil are prescribed more than the recommended maximum amount, according to new research. Wrong Hydroxychloroquine Dose Is Common, Putting Eyes at Risk.. Hydroxychloroquine Plaquenil Side Effects & Dosage for Malaria. Long-Term Side Effects of Plaquenil for Rheumatoid.. This means that the side effects of Plaquenil are mild and infrequent compared with its potential benefits. As with any medication, allergic reactions including skin rashes and non-allergic reactions can occur. The side effect that is of greatest concern is retinal toxicity. Plaquenil is the brand name for the prescription drug hydroxychloroquine. It's used to treat and prevent malaria infection, and to reduce symptoms and progression of autoimmune diseases such as lupus, rheumatoid arthritis, and others. Malaria is spread by mosquitoes. This condition does not cause symptoms and is reversible with cessation of the medication. The finding of corneal verticillata bares no correlation with retinal toxicity and is not an indication to stop the medication 1. The hallmark of hydroxychloroquine toxicity is bilateral pigmentary retinopathy 1.