I did stop it for 2 weeks early in the treatment due to having to take a coupld other drugs that seemed to give me side effects. I just quit the plaquenil to give my liver a rest at that time. Plaquenil isn a antiparasitic drug with anti-inflammatory affect. Chloroquine mode of autophagy inhibition Could you develop a rash 3 weeks after starting hydroxychloroquine Is plaquenil administered subcutaneously Plaquenil side effects skin If you are taking Plaquenil to treat an inflammatory condition or malaria, you should be aware of the side effects that may occur to your eyes and vision. Plaquenil hydroxychloroquine is in a class of drugs called disease-modifying anti-rheumatic drugs, which are used to decrease inflammation, pain and joint damage. Jan 30, 2018 Hi, I've been taking Plaquenil for many years now and have never experienced any side effects or long term effects. But headache is listed as one of the "mild adverse effects". I would suggest that you try to split the dose as suggested. I've always taken 1 in the AM & 1 at night. Plaquenil is a 6-weeker as far as the benefits are concerned, but it would be more dangerous to stop if you spend a lot of time outside and if this were the summer. If you're gonna experiment, I went off it cold turkey as it didn't hurt to do it that way, but you better get back on before the summer or you could experience a flare-up. Over the years on this site we have had quite a few people post that they didn't think that the plaquenil was working so they would stop taking it. I have done a lot of research on this drug and haven't run into anybody who has complained of the withdrawal effect. Any side effects from stopping plaquenil Stopping Plaquenil? DailyStrength, Plaquenil side effects question - Scleroderma - Inspire How does plaquenil help autoimmune diseases Hydroxychloroquine may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away headache; dizziness; loss of appetite; nausea; diarrhea; stomach pain; vomiting; skin rash; If you experience any of the following symptoms, call your doctor immediately Hydroxychloroquine MedlinePlus Drug Information. What is the correct way to discontinue use of plaquenil?. Hydroxychloroquine Side Effects Common, Severe, Long Term.. Has anyone had any side effects from STOPPING plaquenil? Also - does anyone have any great ways to prevent virus and illness, when weak? I seem to get cold after cold after cold this year. I had a diagnosis of seronegative RA in 2017. After two years of plaquenil, my disease is in remission and we have me reduced now to only 100mg per day. Along with its needed effects, hydroxychloroquine the active ingredient contained in Plaquenil may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine Drug-induced ocular side effects are back in the spotlight, thanks to the Academy’s revision of its recommendations on screening for retinal toxicity from chloroquine and its analogue hydroxychloroquine Plaquenil. 1. There are hundreds of drugs with potential retinal toxicity—so many that the National Registry of Drug-Induced Ocular Side.