Please review the following URL and make sure that it is spelled correctly. Applies to hydroxychloroquine: oral tablet Along with its needed effects, hydroxychloroquine (the active ingredient contained in Plaquenil) may cause some unwanted effects. Fatal dose of chloroquine Plaquenil and dermatomyositis Caution is advised when using this drug in children because they may be more sensitive to the side effects of the drug. This medication is not recommended for long-term use in children. If a child accidentally takes this medication, even a small amount can be very harmful possibly fatal. Damage to the retina, the light sensitive portion of the inner eye, can occur with long-term use of Plaquenil or chloroquine Aralen. With Plaquenil, however, the most commonly prescribed anti-malarial, this sort of damage occurs only in 1 out of 5,000 people who take the drug for five years or more. Plaquenil is also used for long-term treatment of autoimmune diseases such as rheumatoid arthritis RA and systemic lupus erythmatosis. According to the Mayo Clinic, it can take up to six months' constant use before an effect is seen in RA 1. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known Some side effects of hydroxychloroquine may occur that usually do not need medical attention. Although not all of these side effects may occur, if they do occur they may need medical attention. Long term plaquenil use Longer-Term Use of Plaquenil Protects Against Lupus Flares Lupus., Treating Lupus with Anti-Malarial Drugs Johns Hopkins Lupus. Chloroquine phosphate and primePlaquenil drug action Plaquenil is a slow-acting drug, meaning that it can take up to 6 months to experience the full benefits of this medication, but it is possible for symptoms to improve in as few as 1 or 2 months. Plaquenil and other antimalarials are the key to controlling lupus long-term, and some lupus patients may be on Plaquenil for the rest of their lives. Plaquenil What You Need to Know - Kaleidoscope Fighting Lupus. Long-Term Side Effects of Plaquenil for Rheumatoid.. Plaquenil Oral Uses, Side Effects, Interactions, Pictures.. Plaquenil is the brand name of hydroxychloroquine, a drug used to prevent or treat malaria 2. Plaquenil is also used for long-term treatment of autoimmune diseases such as rheumatoid arthritis RA and systemic lupus erythmatosis. According to the Mayo Clinic, it can take up to six months' constant use before an effect is seen in RA 1. Re Methotrexate vs Plaquenil side effects long term and short term The MTX dose for autoimmune disease is about 1/1000 the dose they use in cancer patients. MTX also has a long clinical history, which makes it a trustworthy drug, they'll be no "surprise" side effects. Aug 15, 2017 The ICD-10 section that covers long-term drug therapy is Z79, with many subsections and specific diagnosis codes. Because Plaquenil does not have its own specific category, clinicians should use Z79.899—Other Long Term Current Drug Therapy. But getting the right code is just one step in the process of correctly documenting the encounter.