Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known Some side effects of hydroxychloroquine may occur that usually do not need medical attention. Benefits of plaquenil and rheumatoid arthritis Plaquenil causing low wbc count Does plaquenil cause eye problems Chloroquine agarose gel electrophoresis Hydroxychloroquine is generally considered to be the safest DMARD, and a “go to” drug for pregnancy. Retinal pigment changes and retinal toxicity can occur with prolonged use. Early changes tend to be reversible but may progress despite discontinuation if advanced. Abstract. Background The American Academy of Ophthalmology recommendations on screening for chloroquine CQ and hydroxychloroquine HCQ retinopathy are revised in light of new information about the prevalence of toxicity, risk factors, fundus distribution, and effectiveness of screening tools. Pattern of Retinopathy Although the locus of toxic damage is parafoveal in many eyes, Asian. Patients with pre-existing retinopathy of the eye — this is a relative contraindication in that it makes patient monitoring more difficult. Tell me more about hydroxychloroquine. Hydroxychloroquine has a lower risk of ocular toxicity, both corneal and retinal, compared with chloroquine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. Hydroxychloroquine toxicity monitoring HYDROXYCHLOROQUINE Shared Care Guideline V1, Recommendations on Screening for Chloroquine and. Mylan generic plaquenilChloroquine mwTreating lupus with plaquenilHow to code for plaquenil eye examPlaquenil hydroxychloraquine doseage The British Society for Rheumatology BSR has published updated guidelines on the prescribing and monitoring of DMARDs, which include recommendations for more intensive screening for retinal toxicity in patients on antimalarials. Monitoring for retinal toxicity in patients taking hydroxychloroquine.. Hydroxychloroquine DermNet NZ. RETINA PEARLS Monitoring for Hydroxychloroquine Retinal.. Diagnosis Hydroxychloroquine-induced retinal toxicity Discussion. Chloroquine CQ and hydroxychloroquine Plaquenil HCQ have been used for many years, initially for the treatment of malaria but now more commonly for the treatment of inflammatory diseases such as rheumatoid arthritis and lupus 1. Once retinal toxicity from hydroxychloroquine occurs, it is thought that the retinal changes are permanent and the disease can progress even if hydroxychloroquine is stopped for 1 to 3 years. Newer techniques for evaluation of retinal disease have been developed and these techniques can detect retinal toxicity earlier. This article is from June 2011 and may contain outdated material. Download PDF. Many systemic medications may cause retinal toxicity. One such commonly used medication for dermatologic and rheumatologic inflammatory conditions is hydroxychloroquine Plaquenil, a chloroquine derivative.