While the exact percentage of RA patients who experience sleep problems is hard to nail down, more than 80% of people with RA report fatigue as part of their symptoms. Why Sleep Matters Sleep problems can increase levels of stress hormones and aggravate flares, says Rochelle Rosian, MD, a Cleveland Clinic rheumatologist. Clinical trials cancer chloroquine Plaquenil heat Jan 18, 2009 Plaquenil doesn't usually cause insomnia. It is most likely something else, such as prednisone if you're taking it or anxiety. Insomnia is a common complaint for people with Lupus, some as a result of the steroids and some from general stress of the disease. Plaquenil gave me anxiety and I could not sleep while taking a higher dose. You should probably call your doctor and tell them. Maybe they can adjust your milligrams to a lower dose to see if that is what is causing the insomnia. It is no fun not to be able to sleep, i hope you get this figured out and get some rest - Hydroxychloroquine Plaquenil is considered a disease-modifying anti-rheumatic drug DMARD. It can decrease the pain and swelling of arthritis. It may prevent joint damage and reduce the risk of long-term disability. Hydroxychloroquine is in a class of medications that was first used to prevent and treat malaria. “When you sleep, you make all those brain chemicals that you need to feel better. And even if you’re not flaring, you may not manage your pain as well if you’re not sleeping. Plaquenil and insomnia PLAQUENIL Side Effects, Reviews by Patients -, Insomnia and Plaquenil? - Sjogren's World What is the cost of plaquenilPlaquenil price in u.s.aHydroxychloroquine programPlaquenil cognitive side effects Medical usesHistorySide effectsMechanism of actionResultsAdministrationRisksDiagnosisInteractionsPreventionBenefits Taking Plaquenil for Rheumatoid Arthritis. Hydroxychloroquine Plaquenil. Started taking Plaquenil for Lupus and now I can't sleep.. Lupus-Induced Insomnia and a Feeling of Isolation. June 7, 2017 June 7, 2017. by Kristiana Page. In Columns, The Girl Who Cried Wolf - A Column by Kristi Page. Click here to subscribe to the Lupus News Today Newsletter. 0 0 Part of living with lupus is knowing that your body lives outside of the norm. It means accepting that, for the most. What Is Plaquenil? Plaquenil hydroxychloroquine is an antimalarial medication used to treat or prevent malaria, a disease caused by parasites, which enter the body through the bite of a mosquito. Plaquenil is also used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. Plaquenil is available in generic form. What Are Side Effects of Plaquenil? Treatment includes artificial tears and saliva and, in more severe cases, immune blockers such as prednisone, Plaquenil and even the cancer medication Methotrexate. Jacob Teitelbaum, MD. Print. Comments. The news has been buzzing about Venus Williams dropping out of the US Open because of Sjogren's syndrome. as the combination of insomnia.