It's used to treat and prevent malaria infection, and to reduce symptoms and progression of autoimmune diseases such as lupus, rheumatoid arthritis, and others. Malaria is spread by mosquitoes, which transmit the parasites that cause the infection, usually in tropical and subtropical parts of the world. Plaquenil reduction Medication similar to plaquenil Medication for lupus hydroxychloroquine This content was created by the National Sleep Foundation We all feel tired sometimes, but roughly 20 percent of the population can be classified as having Excessive Sleepiness sometimes referred to as Excessive Daytime Sleepiness. Excessive sleepiness is the leading complaint of patients who visit sleep clinics. Hydroxychloroquine Plaquenil is considered a disease-modifying anti-rheumatic drug DMARD. It can decrease the pain and swelling of arthritis. It may prevent joint damage and reduce the risk of long-term disability. Hydroxychloroquine is in a class of medications that was first used to prevent and treat malaria. Other things that alter sleep are sleep apnea steroid weight gain can bring this on. So it's not as simple as just the Plaquenil. Or it could be the Plaquenil AND one of these other things. Many patients with fibro take a "cocktail" at night of a tri-cyclic antidepression the old kind before Prozac + muscle relaxant + restless leg med. For example, it may be combined with an antibiotic to treat chronic Q-fever, which humans usually catch from farm animals or raw milk. Plaquenil is used to treat other types of infections too. Plaquenil and sleepiness Ask the Expert Plaquenil and Sjögren’s, Hydroxychloroquine Plaquenil What are the most common side effects of plaquenilPlaquenil retinopathy oct imagesPlaquenil and vaccinesChloroquine lysosomal degradation Plaquenil and Drowsiness - from FDA reports Summary Drowsiness is found among people who take Plaquenil, especially for people who are female, 50-59 old, have been taking the drug for 1 month, also take medication Enbrel, and have Pain. Will you have Drowsiness with Plaquenil - eHealthMe. Insomnia because of plaquenil DailyStrength. Hydroxychloroquine Side Effects, Dosage, Uses, and More. Hydroxychloroquine Plaquenil and generics can itself cause fatigue in some users, it can interrupt sleep patterns especially by causing more vivid dreams which in turn makes one more tired. The drug can also lower blood counts red cell, white cells and others too which in turn can cause fatigue. Nov 09, 2018 Hydroxychloroquine is used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Malaria is common in areas such as Africa, South America, and Southern Asia. This medicine is not effective against all strains of malaria. Hi Phoebe, I have been on plaquenil for many years and have not experienced a sudden onset of fatigue after taking it. While those of us with lupus never truly find anything to relieve fatigue, plaquenil is suppose to help with fatigue rather than create more from what I understand.