This information should not take the place of medical care and advice from your healthcare providers. Hydroxychloroquine is a medication used to prevent and treat malaria and to treat autoimmune conditions such as rheumatoid arthritis or lupus. Hydroxychloroquine nutrient interactions michigan What drug class is hydroxychloroquine Chloroquine or hydroxychloroquine are considered safe to use in all trimesters of pregnancy. Mefloquine is the agent of choice for chloroquine-resistant areas, and evidence suggests it is not associated with an increased risk to the fetus. Chloroquine, extensively used in pregnancy, is generally thought to be safe for mother and fetus at the therapeutically recommended dose.2 Treatment of Plasmodium falciparum malaria in pregnancy in Kenya3 and Tanzania 4 have indicated the drug to be safe, although with the problem of treatment failure because of parasite resistance. Anti-malarial drugs hydroxychloroquine, chloroquine are considered pregnancy category C drugs. While there is evidence of risk for damage to the eye and ear, if the benefits of these drugs in controlling RA symptoms are judged to outweigh the risks, they may continue to be used during pregnancy. 1,2 For more information on rheumatoid arthritis or lupus in pregnancy please see the Mother To Baby fact sheet on those topics at: https://mothertobaby.org/fact-sheets/rheumatoid-arthritis/pdf or https://mothertobaby.org/fact-sheets/lupus-pregnancy/pdf/. Hydroxychloroquine is sold under several brand names, including Plaquenil®. Chloroquine in early pregnancy Methotrexate and Pregnancy Is It Safe If You Have RA?, Antimalarial drugs and pregnancy safety, pharmacokinetics. Hydroxychloroquine vs chloroquinePlaquenil 200 mg obat apaWhat is toxic dose of plaquenilMechanism of chloroquine resistanceChloroquine ph For pregnant women diagnosed with uncomplicated malaria caused by chloroquine-resistant P. falciparum infection, women in the second and third trimesters can be treated with artemether-lumfantrine, and for all trimesters, mefloquine or a combination of quinine sulfate and clindamycin is recommended. Quinine treatment should continue for 7 days for infections acquired in Southeast Asia and for 3 days for infections acquired elsewhere; clindamycin treatment should continue for 7 days. Treatment of Malaria Guidelines For Clinicians United.. Drug Safety in Pregnant & Nursing Women.. Chloroquine MedlinePlus Drug Information. Chloroquine has not been formally assigned to a pregnancy category by the FDA. There are no controlled data in human pregnancies. Congenital anomalies were reported in the offspring of one woman being treated with chloroquine 250 to 500 mg daily during pregnancy for SLE; however, chloroquine has been used in the prophylaxis and treatment of malaria during pregnancy without evidence of fetal harm. Chloroquine and proguanil usually combined can be used in pregnancy, but may not offer enough protection against malaria in many regions, including Africa. You'll also need to take a 5mg supplement of folic acid if you're taking proguanil. If you're in the first 12 weeks of pregnancy. In the last, LC3 and P62 were also observed in normal human proliferative, secretory, and decidua tissues. In conclusion, endometrial autophagy may be essential for embryo implantation, and it may be associated with endometrial decidualization during early pregnancy. • Autophagy-related markers were significantly decreased at implantation site.