I know its a supposed small risk, but thanks to Google I've uncovered some horror stories about vision issues after just 8mo-1yr and people swearing it is actually not uncommon. I've had the worst flare of my life over late summer, I've had 3 early miscarriages in 1.5 years, I'm almost always in some type of achy state or dead tired. Potential side effects and very real risks make the medication seem ridiculously dangerous. I'm not as familiar with MCTD but what I do know is that is can be just as dangerous as SLE. Is the vision loss something that will stop if the medication is stopped? Plaquenil ceftriaxone interaction Plaquenil guidelines 2018 I'm back on it and waiting the 3-4 months it takes to work at least that's how long it took the first time. I have a great opthamologist who has assured me he will catch retinal damage before I will ever notice a change in my vision, so as far as I'm concerned, I want to stay on Plaquenil until I'm forced off it. A lot of people have less than 4, or as in my case, more than 4 but spread out over much more than 5 years. So it's very possible for plaquenil to do good without you being considered to have Lupus. I went on plaquenil in 2004 for joint pain, high ANA and pericarditis. With Plaquenil, however, the most commonly prescribed anti-malarial, this sort of damage occurs only in 1 out of 5,000 people who take the drug for five years or more. For this reason though, it is important that you see an ophthalmologist for an exam before starting to take an anti-malarial medication for your lupus. Your external symptoms are a sign that something very wrong is going on inside you. Why in the world would anyone choose to poison themselves? You have a choice to make between letting your disease run rampant and continue to damage your body until it can no longer fight back or using one of the few weapons you have at your disposal to slow it down. Unfortunately, you have to roll the dice and decide which risk you'd rather take. How long is plaquenil good When does the plaquenil kick in? DailyStrength, Plaquenil - Chloroquine phosphate freshwater fishChloroquines impact on society Long term ratings 2.3/5. This is a reivew of how effective Plaquenil hydroxychloroquine sulfate is for Fibromyalgia and for what kind of people. The study is created by eHealthMe from 4 Plaquenil users and is updated continuously. On eHealthMe, you can evaluate side effects and drug interactions from 16 million FDA reports. How effective is Plaquenil for Fibromyalgia by duration.. Treating Lupus with Anti-Malarial Drugs Johns Hopkins.. Lupus Medicines Hydroxychloroquine - Brigham and Women's.. I know I've asked this question before, but with so many new people and so much time that's passed, I thought I'd ask again. How long did it take for Plaquenil to become effective for you? Meaning, when did you start to feel some relief from your lupus symptoms after you started taking. Mark a calendar to help you remember. This drug is usually started 2 weeks before entering the area with malaria. Take it once weekly while in the area, and continue taking it for 4 to 8 weeks after leaving the area or as directed by your doctor. To treat malaria, follow your doctor's instructions. Plaquenil has been a life-saving drug for me, quite literally. I was a mess in 2004-2005 and then a dr put me on Plaquenil, and in 3 weeks most of my symptoms had disappeared.