Plaquenil is used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Malaria is common in areas such as Africa, South America, and Southern Asia. Chloroquine autophagy erythroid Fda approval chloroquine-primaquine Plaquenil nightmares Introduction. Many drugs and medications can affect thyroid function. Thyroid hormone levels can be altered by drugs at many levels including the hypothalamus, thyrotropes in the anterior pituitary gland, synthesis and secretion from the thyroid gland and metabolism of thyroid hormones through deiodination, sulfation and glucuronidation. Feb 14, 2011 I'm recently diagnosed with Lupus and the only medications I'm on are Synthroid and Plaquenil. Less than a month after starting Plaquenil I started having problems with insomnia and some anxiety. I'm still struggling to sleep well without waking up and lying awake for hours. Plaquenil and Synthroid drug interaction Gait disturbance -a study from FDA data Summary Gait disturbance is found among people who take Plaquenil and Synthroid, especially for people who are female, 60+ old, have been taking the drugs for 2 - 5 years, also take medication Humira, and have Dizziness. Plaquenil is also an antirheumatic medicine and is used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. This medicine is not effective against all strains of malaria. Synthroid with plaquenil Plaquenil Hydroxychloroquine - Side Effects, Dosage., Plaquenil - Lupus Chloroquine resistente bakterien disserationLichen planopilaris treatment hydroxychloroquine Does Plaquenil Interact with other Medications? Severe Interactions. These medications are not usually taken together. Consult your healthcare professional e.g. doctor or pharmacist for more in. Plaquenil Oral Interactions with Other Medication. Plaquenil and Synthroid drug interaction Gait disturbance.. Plaquenil Oral Uses, Side Effects, Interactions.. Hi, your medicines like synthroid and cytomel are adding to your high blood pressure problem, so you need to take a review of your prescribing physician to decrease their your TSh is 0.04 which is in lower range can indicate high dose of these drugs. while you should continue the other medicines. hope answer was helpful. The plaquenil gives me such relief that I would continue to take it even if it did interfere with the thyroid meds. By the way, yoga also has been a great benefit. It significantly improves range of motion, decreases inflammation of joints, and helps with overall well being. Apr 10, 2019 Plaquenil is sometimes given only once per week. Choose the same day each week to take this medicine if you are on a weekly dosing schedule. Take Plaquenil with a meal or a glass of milk. To prevent malaria Start taking Plaquenil 2 weeks before entering an area where malaria is common. Continue taking the medicine regularly during your stay.