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Viagra originally developed for

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  1. darkus Well-Known Member

    Viagra originally developed for


    Some of the best inventions and discoveries in the history of civilization have been accidental. Penicillin, Teflon, radioactivity, even your favourite Coca-Cola were all chance discoveries. An accidental invention is one where scientists are trying to find a solution to problem A but chance upon a solution to problem B. This is exactly what happened in the case of mankind's dearly loved drug Viagra, that treats erectile dysfunction. In 1989, chemists at Pfizer's research centre in Kent, England, were working to find a new drug to treat hypertension and angina pectoris (chest pain due to blocked arteries). A new compound that was named Sildenafil (UK92480) was created and subsequently tested on a group of men. Unfortunately, in the clinical trials, the compound failed to have a desired effect on hypertension and did not help in dilating the muscles in the heart. compare levitra In 1953 Dr Norm Larsen, founder of the Rocket Chemical Company, was trying to create a fluid which would prevent nuclear missiles from going rusty. There’s lots of waiting around in a Cold War, and the US government found that their arsenal wasn’t faring well. A group of scientists working at Pfizer's lab in Kent developed a drug called Sildenafil for the treatment of angina. Clinical trials in Swansea found that it had almost no effect on the heart or angina, but quite a pronounced side effect on another organ. Cue a quick brainstorming session by the marketing department, and Viagra soon went on sale across the globe. In 2008, the peak sales year for the drug, Pfizer sold almost $2bn worth of the stuff. The patent has now expired in much of Europe, allowing rival companies to sell their own versions.

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    Oct 20, 2014. Older men like Playboy's Hugh Hefner and actor Michael Douglas have sung the praises of Viagra, but now scientists say the erectile. buy inderal la 80 mg From Velcro to Viagra 10 products that were invented by accident. Clinical trials at the pharmaceutical company Pfizer had originally studied Viagra's use as a. Sep 25, 2018. Originally a medication developed by Pfizer to treat angina pectoris chest. Pfizer called it Viagra and made tens of billions of dollars over the.

    The primary indication of sildenafil is treatment of erectile dysfunction (inability to sustain a satisfactory erection to complete intercourse). Its use is now one of the standard treatments for erectile dysfunction, including for men with diabetes mellitus. Rare but serious adverse effects found through postmarketing surveillance include prolonged erections, severe low blood pressure, myocardial infarction (heart attack), ventricular arrhythmias, stroke, increased intraocular pressure, and sudden hearing loss. Care should be exercised by people who are also taking protease inhibitors for the treatment of HIV infection. Protease inhibitors inhibit the metabolism of sildenafil, effectively multiplying the plasma levels of sildenafil, increasing the incidence and severity of side effects. Those using protease inhibitors are recommended to limit their use of sildenafil to no more than one 25 mg dose every 48 hours. blocker (typically prescribed for hypertension or for urologic conditions, such as benign prostatic hypertrophy) at the same time may lead to low blood pressure, but this effect does not occur if they are taken at least 4 hours apart. Ten years ago this month, the Food and Drug Administration's approval of a little blue pill changed the sex lives of millions of men and women. Viagra, the first oral treatment for erectile dysfunction was developed accidentally by scientists at Pfizer Laboratories and was greenlighted for use by the FDA on March 27, 1998."Originally, we were testing sildenafil, the active drug in Viagra, as a cardiovascular drug and for its ability to lower blood pressure,'' Dr. Brian Klee, senior medical director at Pfizer, told French news agency, AFP. "But one thing that was found during those trials is that people didn't want to give the medication back because of the side effect of having erections that were harder, firmer and lasted longer.'' Since its approval, Viagra has been used by 35 million men around the world. It took the taboo out of impotence — former presidential candidate Bob Dole who suffered from erectile dysfunction after surgery for prostate cancer once appeared in a commercial for the drug — and made it easier to treat.

    Viagra originally developed for

    History of Viagra and how it was discovered by accident Daily Mail., From Velcro to Viagra 10 products that were invented. - History Extra

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  5. Sep 10, 2017. Sildenafil, the active ingredient in Viagra, was originally developed to treat cardiovascular problems. It was meant to dilate the heart's blood.

    • How Viagra was discovered by Pfizer — Quartz
    • I Took Knockoff Viagra Until I Learned What's In It - Tonic
    • Viagra The little blue pill that could - CNN -

    Jan 9, 2015. Here are six products, including Viagra and bubble wrap, which were invented. But it was originally developed as a medicine, which inventor. metoprolol er generic Jan 20, 2010. Viagra's discovery. Even the fastest selling drug of all time, Viagra, is not used for what it was originally intended. It started life as plain old. Mar 24, 2008. was developed accidentally by scientists at Pfizer Laboratories and. "Originally, we were testing sildenafil, the active drug in Viagra, as a.

     
  6. MadeInUSSR XenForo Moderator

    My cousin is having a baby girl, and I seriously can’t wait to spoil her. This past weekend was her baby shower and auntie-to-be got her some dope baby gear (Did you know they have baby wipes heaters now? Naturally I didn’t stop there I had to make her something a little less ordinary, gold and adorable. GOLD BABY MOCCASSIN BOOTIES This is my cuuuutest DIY, yet. Here is what you will need: Baby Booties Pattern 12″ x 12″ Pleather Fabric Leather Laces Thread Needle Rotary Hole Puncher Scissors Other tools: E-600 Glue Pen or Marker I had to hand draw my own pattern, but you don’t! Start by cutting the bootie pattern and trace it twice on the back side of your fabric (make sure to flip over the sole piece for the right side bootie). You can print this pattern and use for your baby booties. Now cut your pieces, and set the extra fabric aside. Using the rotary hole puncher, cut the marked circles on the heel piece and cut the two lines on the front piece. Sew the heel piece with the sole piece (leather facing in). Now sew the front piece on to the sole piece, over lapping into the heel piece at each end. You can leave them as is, or do as I did and make them Moccasin Baby Booties. Using extra fabric cut out two 1″ x 2″ pieces, then cut 1″ slices across to create fringe for that moccasin look. Buy robaxin Online - Order Medication Online Antibiotics. buy cialis online fast shipping Buy Robaxin online, How many robaxin to get high Buy online — The International Center for Bathroom
     
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  8. victotr Well-Known Member

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